Detalhe da pesquisa
1.
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell
; 161(3): 501-512, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25865481
2.
Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry
; 60(16): 1243-1247, 2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33829766
3.
Crystal Structure of a ligand-bound LacY-Nanobody Complex.
Proc Natl Acad Sci U S A
; 115(35): 8769-8774, 2018 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108145
4.
Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proc Natl Acad Sci U S A
; 113(17): 4711-6, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27078104
5.
A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer.
Biochemistry
; 57(19): 2786-2795, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29717875
6.
Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site.
Proc Natl Acad Sci U S A
; 112(29): 9004-9, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26157133
7.
Structure of sugar-bound LacY.
Proc Natl Acad Sci U S A
; 111(5): 1784-8, 2014 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24453216
8.
Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.
Proc Natl Acad Sci U S A
; 111(29): 10404-10, 2014 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24994900
9.
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Proc Natl Acad Sci U S A
; 111(10): 3865-70, 2014 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24613931
10.
The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs.
Nucleic Acids Res
; 42(3): 2037-48, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24214967
11.
The unfolded protein response signals through high-order assembly of Ire1.
Nature
; 457(7230): 687-93, 2009 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19079236
12.
EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins.
Proc Natl Acad Sci U S A
; 108(33): 13450-5, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21795602
13.
Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.
J Am Chem Soc
; 135(20): 7583-92, 2013 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23611499
14.
Structural context shapes the aquaporin selectivity filter.
Proc Natl Acad Sci U S A
; 107(40): 17164-9, 2010 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20855585
15.
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat Struct Mol Biol
; 30(3): 296-308, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36782050
16.
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
bioRxiv
; 2023 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747776
17.
A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase.
J Am Chem Soc
; 134(42): 17722-30, 2012 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23034004
18.
Structural and functional basis for RNA cleavage by Ire1.
BMC Biol
; 9: 47, 2011 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21729333
19.
Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1.
BMC Biol
; 9: 48, 2011 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21729334
20.
Diversity of function and mechanism in a family of organic anion transporters.
Curr Opin Struct Biol
; 75: 102399, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35660266